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Ä¡±Ù´Ü º´º¯ÀÌ ÀÖ´Â ¹Ì¼º¼÷ ¿µ±¸Ä¡¿¡¼­ Platelet-rich fibrin(PRF)¸¦ ÀÌ¿ëÇÑ º¸Á¸Àû ±Ù°üÄ¡·á

REGENERATIVE ENDODONTIC TREATMENT OF IMMATURE PERMANENT TEETH BY USING PLATELET-RICH FIBRIN

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±èÇϳª, À̳­¿µ, ÀÌ»óÈ£,
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±èÇϳª ( Kim Ha-Na ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
À̳­¿µ ( Lee Nan-Young ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
ÀÌ»óÈ£ ( Lee Sang-Ho ) - Á¶¼±´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

¼ºÀå ÁßÀÎ ¾Æµ¿¿¡¼­´Â Ä¡±ÙÀÇ ¼ºÀåÀÌ °è¼ÓµÊ¿¡ µû¶ó Ä¡¼ö°¡ ±«»çµÇ¾î Ä¡±ÙÀÇ º´º¯ÀÌ ÀÖ´Â ¹Ì¼º¼÷ ¿µ±¸Ä¡¿¡¼­µµ Ä¡¼öÀÇ ÀçÇ÷°üÈ­°¡ ½ÇÁ¦·Î ÀϾ ¼ö ÀÖ´Ù´Â °¡´É¼ºÀÌ Á¦½Ã µÇ°í ÀÖ´Ù. Ä¡¼öÀÇ ÀçÇ÷°üÈ­¸¦ À§Çؼ­´Â ±Ù°ü ³»ÀÇ °¨¿°ÀÇ Á¶Àý°ú ÇÔ²² ÀûÀýÇÑ scaffold°¡ ÇÊ¿äÇϸç, platelet-rich plasma(PRP)°¡ ÀÌ»óÀûÀÎ scaffold·Î Á¦½ÃµÇ¾ú´Ù. ÃÖ±Ù ÀÓ»ó¿¡¼­´Â PRPÀÇ ´ÜÁ¡À» ±Øº¹ÇÑ platelet-rich fibrin(PRF)°¡ ÀÀ¿ëµÇ°í ÀÖ´Ù. º» Áõ·Ê¿¡¼­´Â Ä¡¿ÜÄ¡ÀÇ ±³µÎ ÆÄÀý·Î ÀÎÇÑ Ä¡¼ö °¨¿°À¸·Î Ä¡±Ù´Ü º´º¯À» °¡Áø ¹Ì¼º¼÷ ¿µ±¸Ä¡ÀÇ ±Ù°ü ³»¿¡ ciprofloxacin, metronidazole, minocyclineÀÇ ¼¼ °¡Áö Ç×»ýÁ¦ Àû¿ë ÈÄ ÀÌ¿Í ÇÔ²² PRF¸¦ Àû¿ëÇÏ¿´´Ù. Á¤±âÀûÀÎ °ËÁø °á°ú Ä¡±Ù´Ü º´º¯ÀÇ Ä¡À¯¿Í ÇÔ²² Ä¡±Ù ¼ºÀåÀÌ °üÂûµÇ¾ú´Ù. ÀÌ·¯ÇÑ º¸Á¸ÀûÀÎ ±Ù°ü Ä¡·á´Â ¹Ì¼º¼÷ ¿µ±¸Ä¡¿¡¼­ Ä¡±Ù´Ü Çü¼º¼úÀÇ ´ë¾ÈÀûÀÎ Ä¡·á·Î¼­ ÀÌ¿ëµÉ ¼ö ÀÖÀ» °ÍÀ̸ç, ÇâÈÄ Àå±â°£ÀÇ ÀÓ»óÀû °üÂûÀÌ ÇÊ¿äÇÒ °ÍÀÌ´Ù.

In case of an immature tooth with necrotic pulp, regeneration of pulp tissue into a canal would be the ideal outcome. It may be capable of promoting the continuation of normal root development. Platelet-rich fibrin has been suggested as a potentially ideal scaffold for regenerative endodontic treatment. Immature permanent teeth of young children were diagnosed with pulp necrosis and apical abscess as the result of clinical and radiographic examination. After removal of necrotic pulp, canal was irrigated with 5.25% NaOCl and dried with paper point. A triple antibiotic mixture was placed in canal space in 3 weeks. After removal of the antibiotic mixture, the platelet-rich fibrin was injected into the canal space with MTA placed directly over the platelet-rich fibrin clot. The coronal region was restored by composite resin. On the basis of short-term results of the present 3 cases, regeneration of vital tissues appears to be possible in a tooth with necrotic pulp and a periapical lesion. Also, platelet-rich fibrin proves to be potentially an ideal scaffold for this procedure. Therefore, long-term clinical observation and examination about this treatment using platelet-rich fibrin in immature permanent teeth of young children are considered to be necessary.

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Regenerative endodontic treatment; Triple antibiotic mixture; Platelet-rich fibrin(PRF)

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